The Viper® Ultrasonic Pharmacomechanical Thrombolysis System is a minimally invasive device designed to dissolve thrombi by combining targeted ultrasonic waves with controlled tPA infusion. By thinning fibrin and increasing clot porosity, the system enables deeper drug penetration into the thrombus, thereby enhancing the efficacy of pharmacological therapy. This approach helps mitigate potential bleeding complications and preserves vessel integrity, offering a more refined, patient-centric strategy for acute thrombosis management.
Ultrasonic Wave Delivery
•Controlled Ultrasound: Low-power ultrasonic energy focuses on fibrin disruption, loosening the structural integrity of the clot.
•Enhanced Porosity: Breaking fibrin strands encourages tPA to penetrate deeper, ensuring thorough thrombus dissolution.
Pharmacomechanical Infusion
•tPA Administration: A site-specific delivery of tissue plasminogen activator (tPA) directly into the clot.
•Synergistic Effect: Ultrasonic micro-cavitation augments the fibrinolytic effect, requiring lower drug doses and potentially reducing hemorrhagic complications.
Gentle Mechanization
•Minimal Vessel Trauma: Ultrasonic waves are calibrated to avoid damaging valves, vessel walls, or critical structures within the venous or pulmonary vasculature.
•Reduced Bleeding Risk: Lower overall drug usage and localized infusion can curtail systemic side effects.
Product Specifications
| Specification | Detail / Value |
| Product Name | Viper ULTRA Thrombolysis Catheter |
| Intended Use | Catheter-directed infusion of thrombolytics in acute or subacute thrombus (peripheral, venous, or arterial) |
| Catheter Design | Multi-hole distal segment for uniform drug dispersion, possible radiopaque marker at tip |
| Material | Pebax/Polyamide shaft, potentially braided or reinforced |
| Outer Diameter (F) | ~4–6F (depending on infusion lumen capacity) |
| Working Length | ~80–150 cm (varies by product code) |
| Infusion Ports | Distributed side ports over a defined segment for consistent thrombolytic delivery |
| Guidewire Compatibility | Typically 0.014” or 0.018” |
| Sterility | Sterile, Single Use |
| Shelf Life | ~2–3 years if stored at 15–25 °C in sealed packaging |
| Clinical Indications | Thrombolytic infusion for DVT, peripheral arterial occlusions, possibly for intra-graft thrombosis |
| Contraindications | Highly calcified lesions, severe vessel tortuosity preventing safe passage, known device material allergies |
Ordering & Size Matrix
| Outer Diameter (F) | Working Length (cm) | Infusion Segment (cm) | Product Code | Notes |
| 4F | 80 | 10 | VPR-4F-80-10 | Smaller OD for distal or small vessel usage |
| 4F | 120 | 15 | VPR-4F-120-15 | Longer shaft, moderate infusion segment |
| 5F | 80 | 10 | VPR-5F-80-10 | Slightly larger OD for heavier clot load |
| 5F | 120 | 20 | VPR-5F-120-20 | Extended length with longer infusion zone |
| 6F | 100 | 15 | VPR-6F-100-15 | Common size for multi-level peripheral lesions |
| 6F | 150 | 30 | VPR-6F-150-30 | Max length, extensive infusion segment |
